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LC3-positive structures are prominent in autophagy-deficient cells

Autophagy is an evolutionarily conserved process across eukaryotes that degrades cargoes like aggregate-prone proteins, pathogens, damaged organelles and macromolecules via delivery to lysosomes. The process involves the formation of double-membraned autophagosomes that engulf the cargoes destined f...

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Detalles Bibliográficos
Autores principales: Runwal, Gautam, Stamatakou, Eleanna, Siddiqi, Farah H., Puri, Claudia, Zhu, Ye, Rubinsztein, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625982/
https://www.ncbi.nlm.nih.gov/pubmed/31300716
http://dx.doi.org/10.1038/s41598-019-46657-z