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LC3-positive structures are prominent in autophagy-deficient cells
Autophagy is an evolutionarily conserved process across eukaryotes that degrades cargoes like aggregate-prone proteins, pathogens, damaged organelles and macromolecules via delivery to lysosomes. The process involves the formation of double-membraned autophagosomes that engulf the cargoes destined f...
Autores principales: | Runwal, Gautam, Stamatakou, Eleanna, Siddiqi, Farah H., Puri, Claudia, Zhu, Ye, Rubinsztein, David C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625982/ https://www.ncbi.nlm.nih.gov/pubmed/31300716 http://dx.doi.org/10.1038/s41598-019-46657-z |
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