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Increased LIGHT leading to sFlt-1 elevation underlies the pathogenic link between hydatidiform mole and preeclampsia

Hydatidiform moles are known to pose an extremely high risk of severe early-onset preeclampsia if left untreated. TNF superfamily cytokine, LIGHT has recently been reported to contribute to pathophysiology of preeclampsia. The present study aimed to investigate the involvement of LIGHT in hydatidifo...

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Detalles Bibliográficos
Autores principales: Iriyama, Takayuki, Wang, Guan, Yoshikawa, Midori, Mimura, Nobuko, Matsui, Haruka, Sayama, Seisuke, Kumasawa, Keiichi, Nagamatsu, Takeshi, Koga, Kaori, Kotani, Tomomi, Niimi, Kaoru, Yamamoto, Eiko, Kellems, Rodney E., Xia, Yang, Osuga, Yutaka, Fujii, Tomoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625991/
https://www.ncbi.nlm.nih.gov/pubmed/31300808
http://dx.doi.org/10.1038/s41598-019-46660-4