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Differential effects of slow rewarming after cerebral hypothermia on white matter recovery after global cerebral ischemia in near-term fetal sheep

It is widely believed that rewarming slowly after therapeutic hypothermia for hypoxic-ischemic (HI) encephalopathy can improve outcomes, but its impact on white matter injury after HI is unclear. Fetal sheep (0.85 gestation) received 30 min ischemia-normothermia (n = 8), or hypothermia from 3–48 h w...

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Detalles Bibliográficos
Autores principales: Draghi, V., Wassink, G., Zhou, K. Q., Bennet, L., Gunn, A. J., Davidson, J. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626025/
https://www.ncbi.nlm.nih.gov/pubmed/31300687
http://dx.doi.org/10.1038/s41598-019-46505-0