Molecular basis of egg coat cross-linking sheds light on ZP1-associated female infertility

Mammalian fertilisation begins when sperm interacts with the egg zona pellucida (ZP), whose ZP1 subunit is important for fertility by covalently cross-linking ZP filaments into a three-dimensional matrix. Like ZP4, a structurally-related component absent in the mouse, ZP1 is predicted to contain an...

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Detalles Bibliográficos
Autores principales: Nishimura, Kaoru, Dioguardi, Elisa, Nishio, Shunsuke, Villa, Alessandra, Han, Ling, Matsuda, Tsukasa, Jovine, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626044/
https://www.ncbi.nlm.nih.gov/pubmed/31300655
http://dx.doi.org/10.1038/s41467-019-10931-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626044/
https://www.ncbi.nlm.nih.gov/pubmed/31300655
http://dx.doi.org/10.1038/s41467-019-10931-5

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