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Anti-androgenic therapy with finasteride in patients with chronic heart failure - a retrospective propensity score based analysis

Sex hormones influence the prevalence and the outcome of heart diseases. The conversion of testosterone to its more active metabolite dihydrotestosterone drives cardiac growth and dysfunction, while inhibition of this step by the anti-androgenic drug finasteride counteracts these pathological proces...

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Detalles Bibliográficos
Autores principales: Kattih, Badder, Elling, Lukas Simon, Weiss, Christel, Bea, Marieke, Zwadlo, Carolin, Bavendiek, Udo, Bauersachs, Johann, Heineke, Joerg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626053/
https://www.ncbi.nlm.nih.gov/pubmed/31300720
http://dx.doi.org/10.1038/s41598-019-46640-8