Evaluation of in silico designed inhibitors targeting MelF (Rv1936) against Mycobacterium marinum within macrophages

We recently identified inhibitors targeting Mycobacterium marinum MelF (Rv1936) by in silico analysis, which exhibited bacteriostatic/bactericidal activity against M. marinum and M. tuberculosis in vitro. Herein, we evaluated the effect of best four inhibitors (# 5175552, # 6513745, # 5255829, # 912...

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Detalles Bibliográficos
Autores principales: Dharra, Renu, Radhakrishnan, V. S., Prasad, Tulika, Thakur, Zoozeal, Cirillo, Jeffrey D., Sheoran, Abhishek, Pandey, Amit K., Kulharia, Mahesh, Mehta, Promod K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626058/
https://www.ncbi.nlm.nih.gov/pubmed/31300732
http://dx.doi.org/10.1038/s41598-019-46295-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626058/
https://www.ncbi.nlm.nih.gov/pubmed/31300732
http://dx.doi.org/10.1038/s41598-019-46295-5

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