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Impact of genome architecture on the functional activation and repression of Hox regulatory landscapes

BACKGROUND: The spatial organization of the mammalian genome relies upon the formation of chromatin domains of various scales. At the level of gene regulation in cis, collections of enhancer sequences define large regulatory landscapes that usually match with the presence of topologically associatin...

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Detalles Bibliográficos
Autores principales: Rodríguez-Carballo, Eddie, Lopez-Delisle, Lucille, Yakushiji-Kaminatsui, Nayuta, Ullate-Agote, Asier, Duboule, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626364/
https://www.ncbi.nlm.nih.gov/pubmed/31299961
http://dx.doi.org/10.1186/s12915-019-0677-x