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Impact of genome architecture on the functional activation and repression of Hox regulatory landscapes
BACKGROUND: The spatial organization of the mammalian genome relies upon the formation of chromatin domains of various scales. At the level of gene regulation in cis, collections of enhancer sequences define large regulatory landscapes that usually match with the presence of topologically associatin...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626364/ https://www.ncbi.nlm.nih.gov/pubmed/31299961 http://dx.doi.org/10.1186/s12915-019-0677-x |