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CCAAT/enhancer-binding protein delta regulates the stemness of glioma stem-like cells through activating PDGFA expression upon inflammatory stimulation

BACKGROUND: The small population of glioma stem-like cells (GSCs) contributes to tumor initiation, malignancy, and recurrence in glioblastoma. However, the maintenance of GSC properties in the tumor microenvironment remains unclear. In glioma, non-neoplastic cells create an inflammatory environment...

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Detalles Bibliográficos
Autores principales: Wang, Shao-Ming, Lin, Hong-Yi, Chen, Yen-Lin, Hsu, Tsung-I, Chuang, Jian-Ying, Kao, Tzu-Jen, Ko, Chiung-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626372/
https://www.ncbi.nlm.nih.gov/pubmed/31300060
http://dx.doi.org/10.1186/s12974-019-1535-z