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Matrine inhibits IL-1β secretion in primary porcine alveolar macrophages through the MyD88/NF-κB pathway and NLRP3 inflammasome

Our previous studies demonstrated that matrine directly acts on the replication process of porcine reproductive and respiratory syndrome virus (PRRSV). Matrine inhibits viral replication and is also associated with the NF-κB signalling pathway. These results suggest that matrine has antiviral and an...

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Detalles Bibliográficos
Autores principales: Sun, Panpan, Sun, Na, Yin, Wei, Sun, Yaogui, Fan, Kuohai, Guo, Jianhua, Khan, Ajab, He, Yongming, Li, Hongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626430/
https://www.ncbi.nlm.nih.gov/pubmed/31300043
http://dx.doi.org/10.1186/s13567-019-0671-x