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Plasma exosomes from children with juvenile dermatomyositis are taken up by human aortic endothelial cells and are associated with altered gene expression in those cells

BACKGROUND: The pathology of juvenile dermatomyositis (JDM) is characterized by prominent vessel wall and perivascular inflammation. This feature of the disease has remained unexplained and under-investigated. We have hypothesized that plasma exosomes, which play an important role in inter-cellular...

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Detalles Bibliográficos
Autores principales: Jiang, Kaiyu, Karasawa, Rie, Hu, Zihua, Chen, Yanmin, Holmes, Lucy, O’Neil, Kathleen M., Jarvis, James N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626431/
https://www.ncbi.nlm.nih.gov/pubmed/31299993
http://dx.doi.org/10.1186/s12969-019-0347-0