PKM2 coordinates glycolysis with mitochondrial fusion and oxidative phosphorylation

A change in the metabolic flux of glucose from mitochondrial oxidative phosphorylation (OXPHOS) to aerobic glycolysis is regarded as one hallmark of cancer. However, the mechanisms underlying the metabolic switch between aerobic glycolysis and OXPHOS are unclear. Here we show that the M2 isoform of...

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Detalles Bibliográficos
Autores principales: Li, Tong, Han, Jinbo, Jia, Liangjie, Hu, Xiao, Chen, Liqun, Wang, Yiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626593/
https://www.ncbi.nlm.nih.gov/pubmed/30887444
http://dx.doi.org/10.1007/s13238-019-0618-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626593/
https://www.ncbi.nlm.nih.gov/pubmed/30887444
http://dx.doi.org/10.1007/s13238-019-0618-z

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