A miRNA-HERC4 pathway promotes breast tumorigenesis by inactivating tumor suppressor LATS1

The E3 ligase HERC4 is overexpressed in human breast cancer and its expression levels correlated with the prognosis of breast cancer patients. However, the roles of HERC4 in mammary tumorigenesis remain unclear. Here we demonstrate that the knockdown of HERC4 in human breast cancer cells dramaticall...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Youqin, Ji, Kaiyuan, Wu, Meng, Hao, Bingtao, Yao, Kai-tai, Xu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626598/
https://www.ncbi.nlm.nih.gov/pubmed/30710319
http://dx.doi.org/10.1007/s13238-019-0607-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626598/
https://www.ncbi.nlm.nih.gov/pubmed/30710319
http://dx.doi.org/10.1007/s13238-019-0607-2

Ejemplares similares