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A miRNA-HERC4 pathway promotes breast tumorigenesis by inactivating tumor suppressor LATS1
The E3 ligase HERC4 is overexpressed in human breast cancer and its expression levels correlated with the prognosis of breast cancer patients. However, the roles of HERC4 in mammary tumorigenesis remain unclear. Here we demonstrate that the knockdown of HERC4 in human breast cancer cells dramaticall...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Higher Education Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626598/ https://www.ncbi.nlm.nih.gov/pubmed/30710319 http://dx.doi.org/10.1007/s13238-019-0607-2 |