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MYB-NFIB gene fusions identified in archival adenoid cystic carcinoma tissue employing NanoString analysis: an exploratory study

BACKGROUND: Adenoid cystic carcinoma (ACC) is a slow growing salivary gland malignancy that is molecularly characterized by t(6:9)(q22–23;p23–24) translocations which predominantly result in MYB-NFIB gene fusions in nearly half of tumours. Detection of MYB-NFIB transcripts is typically performed wit...

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Detalles Bibliográficos
Autores principales: McIntyre, John B., Ko, Jenny J., Siever, Jodi, Chan, Angela M. Y., Simpson, Roderick H. W., Hao, Desiree, Lau, Harold Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626627/
https://www.ncbi.nlm.nih.gov/pubmed/31301736
http://dx.doi.org/10.1186/s13000-019-0855-8