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Improving the Repeatability and Efficacy of Intradermal Electroporated Self-Replicating mRNA
Local administration of naked self-replicating mRNA (sr-mRNA) in the skin or muscle using electroporation is effective but hampered by low repeatability. In this manuscript, we demonstrated that intradermal electroporation of sr-mRNA in combination with a protein-based RNase inhibitor increased the...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626868/ https://www.ncbi.nlm.nih.gov/pubmed/31307005 http://dx.doi.org/10.1016/j.omtn.2019.06.011 |