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Autologous, Gene-Modified Hematopoietic Stem and Progenitor Cells Repopulate the Central Nervous System with Distinct Clonal Variants
Myeloid-differentiated hematopoietic stem cells (HSCs) have contributed to a number of novel treatment approaches for lysosomal storage diseases of the central nervous system (CNS), and may also be applied to patients infected with HIV. We quantified hematopoietic stem and progenitor cell (HSPC) tra...
Autores principales: | Peterson, Christopher W., Adair, Jennifer E., Wohlfahrt, Martin E., Deleage, Claire, Radtke, Stefan, Rust, Blake, Norman, Krystin K., Norgaard, Zachary K., Schefter, Lauren E., Sghia-Hughes, Gabriella M., Repetto, Andrea, Baldessari, Audrey, Murnane, Robert D., Estes, Jacob D., Kiem, Hans-Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626873/ https://www.ncbi.nlm.nih.gov/pubmed/31204301 http://dx.doi.org/10.1016/j.stemcr.2019.05.016 |
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