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Breast Cancer Stem Cells with Tumor- versus Metastasis-Initiating Capacities Are Modulated by TGFBR1 Inhibition

Cancer stem cells (CSCs) are defined by their ability to regenerate a tumor upon transplantation. However, it is not yet clear whether tumors contain a single CSC population or different subsets of cells with mixed capacities for initiating primary and secondary tumors. Using two different identific...

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Detalles Bibliográficos
Autores principales: Fico, Flavia, Bousquenaud, Mélanie, Rüegg, Curzio, Santamaria-Martínez, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626885/
https://www.ncbi.nlm.nih.gov/pubmed/31257133
http://dx.doi.org/10.1016/j.stemcr.2019.05.026