TGF-β Signaling Plays an Essential Role in the Lineage Specification of Mesenchymal Stem/Progenitor Cells in Fetal Bone Marrow

Mesenchymal stromal cells are key components of hematopoietic niches in the bone marrow. Here we abrogated transforming growth factor β (TGF-β) signaling in mesenchymal stem/progenitor cells (MSPCs) by deleting Tgfbr2 in mesenchymal cells using a doxycycline-repressible Sp7 (osterix)-Cre transgene....

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Detalles Bibliográficos
Autores principales: Abou-Ezzi, Grazia, Supakorndej, Teerawit, Zhang, Jingzhu, Anthony, Bryan, Krambs, Joseph, Celik, Hamza, Karpova, Darja, Craft, Clarissa S., Link, Daniel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626889/
https://www.ncbi.nlm.nih.gov/pubmed/31204302
http://dx.doi.org/10.1016/j.stemcr.2019.05.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626889/
https://www.ncbi.nlm.nih.gov/pubmed/31204302
http://dx.doi.org/10.1016/j.stemcr.2019.05.017

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