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Screening miRNAs associated with resistance gemcitabine from exosomes in A549 lung cancer cells

PURPOSE: To establish a gemcitabine-resistant lung adenocarcinoma cell line, A549/G+, and to screen the differences of miRNA expression in exosomes from A549 and A549/G+ cells. METHODS: A549 cells were exposed in gemcitabine until they were resistant to gemcitabine, and extracted exosomes from A549...

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Detalles Bibliográficos
Autores principales: Liang, Ai-Ling, Du, Shen-Lin, Zhang, Bin, Zhang, Jing, Ma, Xuan, Wu, Cui-Yun, Liu, Yong-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626902/
https://www.ncbi.nlm.nih.gov/pubmed/31372037
http://dx.doi.org/10.2147/CMAR.S209149