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Computer Modeling of Clonal Dominance: Memory-Anti-Naïve and Its Curbing by Attrition

Experimental and computational studies have revealed that T-cell cross-reactivity is a widespread phenomenon that can either be advantageous or detrimental to the host. In particular, detrimental effects can occur whenever the clonal dominance of memory cells is not justified by their infection-clea...

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Detalles Bibliográficos
Autores principales: Castiglione, Filippo, Ghersi, Dario, Celada, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626922/
https://www.ncbi.nlm.nih.gov/pubmed/31338096
http://dx.doi.org/10.3389/fimmu.2019.01513