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Computer Modeling of Clonal Dominance: Memory-Anti-Naïve and Its Curbing by Attrition
Experimental and computational studies have revealed that T-cell cross-reactivity is a widespread phenomenon that can either be advantageous or detrimental to the host. In particular, detrimental effects can occur whenever the clonal dominance of memory cells is not justified by their infection-clea...
Autores principales: | Castiglione, Filippo, Ghersi, Dario, Celada, Franco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626922/ https://www.ncbi.nlm.nih.gov/pubmed/31338096 http://dx.doi.org/10.3389/fimmu.2019.01513 |
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