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Protocol: Using N-of-1 tests to identify responders to melatonin for sleep disturbance in Parkinson's disease

BACKGROUND: 40% of Parkinson's Disease (PD) sufferers experience insomnia, impacting health and quality of life for patients and family members, especially carers. There is little evidence that current treatments are effective. OBJECTIVES: To determine the effectiveness of melatonin in reducing...

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Detalles Bibliográficos
Autores principales: Nikles, J., O'Sullivan, J.D., Mitchell, G.K., Smith, S.S., McGree, J.M., Senior, H., Dissanyaka, N., Ritchie, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626998/
https://www.ncbi.nlm.nih.gov/pubmed/31338478
http://dx.doi.org/10.1016/j.conctc.2019.100397