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Protocol: Using N-of-1 tests to identify responders to melatonin for sleep disturbance in Parkinson's disease
BACKGROUND: 40% of Parkinson's Disease (PD) sufferers experience insomnia, impacting health and quality of life for patients and family members, especially carers. There is little evidence that current treatments are effective. OBJECTIVES: To determine the effectiveness of melatonin in reducing...
Autores principales: | Nikles, J., O'Sullivan, J.D., Mitchell, G.K., Smith, S.S., McGree, J.M., Senior, H., Dissanyaka, N., Ritchie, A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626998/ https://www.ncbi.nlm.nih.gov/pubmed/31338478 http://dx.doi.org/10.1016/j.conctc.2019.100397 |
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