Gain of 20q11.21 in Human Pluripotent Stem Cells Impairs TGF-β-Dependent Neuroectodermal Commitment

Gain of 20q11.21 is one of the most common recurrent genomic aberrations in human pluripotent stem cells. Although it is known that overexpression of the antiapoptotic gene Bcl-xL confers a survival advantage to the abnormal cells, their differentiation capacity has not been fully investigated. RNA...

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Detalles Bibliográficos
Autores principales: Markouli, C., De Deckersberg, E. Couvreu, Regin, M., Nguyen, H.T., Zambelli, F., Keller, A., Dziedzicka, D., De Kock, J., Tilleman, L., Van Nieuwerburgh, F., Franceschini, L., Sermon, K., Geens, M., Spits, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627003/
https://www.ncbi.nlm.nih.gov/pubmed/31178415
http://dx.doi.org/10.1016/j.stemcr.2019.05.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627003/
https://www.ncbi.nlm.nih.gov/pubmed/31178415
http://dx.doi.org/10.1016/j.stemcr.2019.05.005

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