Control of Hematopoietic Stem and Progenitor Cell Function through Epigenetic Regulation of Energy Metabolism and Genome Integrity

It remains largely unclear how stem cells regulate bioenergetics and genome integrity to ensure tissue homeostasis. Here, our integrative gene analyses suggest that metabolic and genotoxic stresses may underlie the common functional defects of both fetal and adult hematopoietic stem and progenitor c...

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Detalles Bibliográficos
Autores principales: Yang, Zhenhua, Shah, Kushani, Khodadadi-Jamayran, Alireza, Jiang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627005/
https://www.ncbi.nlm.nih.gov/pubmed/31231026
http://dx.doi.org/10.1016/j.stemcr.2019.05.023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627005/
https://www.ncbi.nlm.nih.gov/pubmed/31231026
http://dx.doi.org/10.1016/j.stemcr.2019.05.023

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