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Cell migration through three-dimensional confining pores: speed accelerations by deformation and recoil of the nucleus

Directional cell migration in dense three-dimensional (3D) environments critically depends upon shape adaptation and is impeded depending on the size and rigidity of the nucleus. Accordingly, the nucleus is primarily understood as a physical obstacle; however, its pro-migratory functions by stepwise...

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Detalles Bibliográficos
Autores principales: Krause, Marina, Yang, Feng Wei, te Lindert, Mariska, Isermann, Philipp, Schepens, Jan, Maas, Ralph J. A., Venkataraman, Chandrasekhar, Lammerding, Jan, Madzvamuse, Anotida, Hendriks, Wiljan, te Riet, Joost, Wolf, Katarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627020/
https://www.ncbi.nlm.nih.gov/pubmed/31431171
http://dx.doi.org/10.1098/rstb.2018.0225