Cortical neurodevelopment in pre-manifest Huntington's disease

BACKGROUND: The expression of the HTT CAG repeat expansion mutation causes neurodegeneration in Huntington's disease (HD). Objectives: In light of the – mainly in-vitro – evidence suggesting an additional role of huntingtin in neurodevelopment we used 3T MRI to test the hypothesis that in CAG-e...

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Detalles Bibliográficos
Autores principales: Kubera, Katharina M., Schmitgen, Mike M., Hirjak, Dusan, Wolf, Robert Christian, Orth, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627026/
https://www.ncbi.nlm.nih.gov/pubmed/31491822
http://dx.doi.org/10.1016/j.nicl.2019.101913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627026/
https://www.ncbi.nlm.nih.gov/pubmed/31491822
http://dx.doi.org/10.1016/j.nicl.2019.101913

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