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Cortical neurodevelopment in pre-manifest Huntington's disease
BACKGROUND: The expression of the HTT CAG repeat expansion mutation causes neurodegeneration in Huntington's disease (HD). Objectives: In light of the – mainly in-vitro – evidence suggesting an additional role of huntingtin in neurodevelopment we used 3T MRI to test the hypothesis that in CAG-e...
Autores principales: | Kubera, Katharina M., Schmitgen, Mike M., Hirjak, Dusan, Wolf, Robert Christian, Orth, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627026/ https://www.ncbi.nlm.nih.gov/pubmed/31491822 http://dx.doi.org/10.1016/j.nicl.2019.101913 |
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