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Probing Multi-Target Action of Phlorotannins as New Monoamine Oxidase Inhibitors and Dopaminergic Receptor Modulators with the Potential for Treatment of Neuronal Disorders

Modulation of multiple protein targets with a single compound is essential for the effective treatment of central nervous system disorders. In our previous G protein-coupled receptor (GPCR) cell-based study, a selective human monoamine oxidase (hMAO)-A inhibitor, eckol, stimulated activity of dopami...

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Detalles Bibliográficos
Autores principales: Seong, Su Hui, Paudel, Pradeep, Choi, Jeong-Wook, Ahn, Dong Hyun, Nam, Taek-Jeong, Jung, Hyun Ah, Choi, Jae Sue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627067/
https://www.ncbi.nlm.nih.gov/pubmed/31238535
http://dx.doi.org/10.3390/md17060377