Cargando…

Mitochondrial DNA Variants and Common Diseases: A Mathematical Model for the Diversity of Age-Related mtDNA Mutations

The mitochondrion is the only organelle in the human cell, besides the nucleus, with its own DNA (mtDNA). Since the mitochondrion is critical to the energy metabolism of the eukaryotic cell, it should be unsurprising, then, that a primary driver of cellular aging and related diseases is mtDNA instab...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Huanzheng, Slone, Jesse, Fei, Lin, Huang, Taosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627076/
https://www.ncbi.nlm.nih.gov/pubmed/31216686
http://dx.doi.org/10.3390/cells8060608