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Inhibition of the Fission Machinery Mitigates OPA1 Impairment in Adult Skeletal Muscles

The maintenance of muscle mass and its ability to function relies on a bioenergetic efficient mitochondrial network. This network is highly impacted by fusion and fission events. We have recently shown that the acute deletion of the fusion protein Opa1 induces muscle atrophy, systemic inflammatory r...

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Detalles Bibliográficos
Autores principales: Romanello, Vanina, Scalabrin, Marco, Albiero, Mattia, Blaauw, Bert, Scorrano, Luca, Sandri, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627087/
https://www.ncbi.nlm.nih.gov/pubmed/31208084
http://dx.doi.org/10.3390/cells8060597