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Indirect Radioiodination of DARPin G3 Using N-succinimidyl-Para-Iodobenzoate Improves the Contrast of HER2 Molecular Imaging

Radionuclide molecular imaging of human epidermal growth factor receptor 2 (HER2) in breast and gastroesophageal cancer might be used to stratify patients for HER2-targeted therapy as well as monitor treatment response and disease progression. Designed ankyrin repeat proteins (DARPins) are small eng...

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Detalles Bibliográficos
Autores principales: Vorobyeva, Anzhelika, Schulga, Alexey, Rinne, Sara S., Günther, Tyran, Orlova, Anna, Deyev, Sergey, Tolmachev, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627094/
https://www.ncbi.nlm.nih.gov/pubmed/31234471
http://dx.doi.org/10.3390/ijms20123047