Hirsutanol A Attenuates Lipopolysaccharide-Mediated Matrix Metalloproteinase 9 Expression and Cytokines Production and Improves Endotoxemia-Induced Acute Sickness Behavior and Acute Lung Injury

Activated human monocytes/macrophages, which increase the levels of matrix metalloproteinases (MMPs) and pro-inflammatory cytokines, are the essential mechanisms for the progression of sepsis. In the present study, we determined the functions and mechanisms of hirsutanolA (HA), which is isolated fro...

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Detalles Bibliográficos
Autores principales: Jan, Jing-Shiun, Yang, Chih-Hao, Wang, Mong-Heng, Lin, Fan-Li, Yen, Jing-Lun, Hsieh, Irene, Khotimchenko, Maksim, Lee, Tzong-Huei, Hsiao, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627105/
https://www.ncbi.nlm.nih.gov/pubmed/31213027
http://dx.doi.org/10.3390/md17060360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627105/
https://www.ncbi.nlm.nih.gov/pubmed/31213027
http://dx.doi.org/10.3390/md17060360

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