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Hirsutanol A Attenuates Lipopolysaccharide-Mediated Matrix Metalloproteinase 9 Expression and Cytokines Production and Improves Endotoxemia-Induced Acute Sickness Behavior and Acute Lung Injury
Activated human monocytes/macrophages, which increase the levels of matrix metalloproteinases (MMPs) and pro-inflammatory cytokines, are the essential mechanisms for the progression of sepsis. In the present study, we determined the functions and mechanisms of hirsutanolA (HA), which is isolated fro...
Autores principales: | Jan, Jing-Shiun, Yang, Chih-Hao, Wang, Mong-Heng, Lin, Fan-Li, Yen, Jing-Lun, Hsieh, Irene, Khotimchenko, Maksim, Lee, Tzong-Huei, Hsiao, George |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627105/ https://www.ncbi.nlm.nih.gov/pubmed/31213027 http://dx.doi.org/10.3390/md17060360 |
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