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From Powerhouse to Perpetrator—Mitochondria in Health and Disease

In this review we discuss the interaction between metabolic stress, mitochondrial dysfunction, and genomic instability. Unrepaired DNA damage in the nucleus resulting from excess accumulation of DNA damages and stalled replication can initiate cellular signaling responses that negatively affect meta...

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Detalles Bibliográficos
Autores principales: Fakouri, Nima B., Hansen, Thomas Lau, Desler, Claus, Anugula, Sharath, Rasmussen, Lene Juel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627154/
https://www.ncbi.nlm.nih.gov/pubmed/31083572
http://dx.doi.org/10.3390/biology8020035