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Starve Cancer Cells of Glutamine: Break the Spell or Make a Hungry Monster?

Distinct from normal differentiated tissues, cancer cells reprogram nutrient uptake and utilization to accommodate their elevated demands for biosynthesis and energy production. A hallmark of these types of reprogramming is the increased utilization of, and dependency on glutamine, a nonessential am...

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Detalles Bibliográficos
Autores principales: Jiang, Jie, Srivastava, Sankalp, Zhang, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627209/
https://www.ncbi.nlm.nih.gov/pubmed/31212591
http://dx.doi.org/10.3390/cancers11060804