Cargando…

Radiosensitization and a Less Aggressive Phenotype of Human Malignant Glioma Cells Expressing Isocitrate Dehydrogenase 1 (IDH1) Mutant Protein: Dissecting the Mechanisms

The presence of an isocitrate dehydrogenase 1 (IDH1) mutation is associated with a less aggressive phenotype, increased sensitivity to radiation, and increased overall survival in patients with diffuse glioma. Based on in vitro experimentations in malignant glioma cell lines, the consequences on cel...

Descripción completa

Detalles Bibliográficos
Autores principales: Kessler, Jacqueline, Hohmann, Tim, Güttler, Antje, Petrenko, Marina, Ostheimer, Christian, Hohmann, Urszula, Bache, Matthias, Dehghani, Faramarz, Vordermark, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627228/
https://www.ncbi.nlm.nih.gov/pubmed/31242696
http://dx.doi.org/10.3390/cancers11060889

Ejemplares similares