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Compound C Inhibits B16-F1 Tumor Growth in a Syngeneic Mouse Model via the Blockage of Cell Cycle Progression and Angiogenesis

We recently observed that Compound C (CompC), a reversible inhibitor of AMP-activated protein kinase, reduced the cell viability of B16-F1 melanoma cells. To establish its molecular mechanism(s) of action, the cell cycle was examined by flow cytometry and the expression of cell cycle regulatory prot...

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Detalles Bibliográficos
Autores principales: Lee, Yun Taek, Lim, So Hyun, Lee, Boram, Kang, Insug, Yeo, Eui-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627246/
https://www.ncbi.nlm.nih.gov/pubmed/31200558
http://dx.doi.org/10.3390/cancers11060823