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Compound C Inhibits B16-F1 Tumor Growth in a Syngeneic Mouse Model via the Blockage of Cell Cycle Progression and Angiogenesis
We recently observed that Compound C (CompC), a reversible inhibitor of AMP-activated protein kinase, reduced the cell viability of B16-F1 melanoma cells. To establish its molecular mechanism(s) of action, the cell cycle was examined by flow cytometry and the expression of cell cycle regulatory prot...
Autores principales: | Lee, Yun Taek, Lim, So Hyun, Lee, Boram, Kang, Insug, Yeo, Eui-Ju |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627246/ https://www.ncbi.nlm.nih.gov/pubmed/31200558 http://dx.doi.org/10.3390/cancers11060823 |
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