Effects of the Pentapeptide P33 on Memory and Synaptic Plasticity in APP/PS1 Transgenic Mice: A Novel Mechanism Presenting the Protein Fe65 as a Target

Regulated intramembrane proteolysis (RIP) of the amyloid precursor protein (APP) leads to the formation of fragments, among which the intracellular domain of APP (AICD) was also identified to be a causative of early pathological events. AICD-counteracting proteins, such as Fe65, may serve as alterna...

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Detalles Bibliográficos
Autores principales: Szögi, Titanilla, Schuster, Ildikó, Borbély, Emőke, Gyebrovszki, Andrea, Bozsó, Zsolt, Gera, János, Rajkó, Róbert, Sántha, Miklós, Penke, Botond, Fülöp, Lívia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627374/
https://www.ncbi.nlm.nih.gov/pubmed/31234498
http://dx.doi.org/10.3390/ijms20123050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627374/
https://www.ncbi.nlm.nih.gov/pubmed/31234498
http://dx.doi.org/10.3390/ijms20123050

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