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Effect of Protein Denaturation and Enzyme Inhibitors on Proteasomal-Mediated Production of Peptides in Human Embryonic Kidney Cells

Peptides produced by the proteasome have been proposed to function as signaling molecules that regulate a number of biological processes. In the current study, we used quantitative peptidomics to test whether conditions that affect protein stability, synthesis, or turnover cause changes in the level...

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Detalles Bibliográficos
Autores principales: Dasgupta, Sayani, Fishman, Michael A., Castro, Leandro M., Tashima, Alexandre K., Ferro, Emer S., Fricker, Lloyd D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627375/
https://www.ncbi.nlm.nih.gov/pubmed/31142026
http://dx.doi.org/10.3390/biom9060207