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Hedgehog Pathway as a Potential Intervention Target in Esophageal Cancer

Esophageal cancer (EC) is an aggressive disease with a poor prognosis. Treatment resistance is a major challenge in successful anti-cancer therapy. Pathological complete response after neoadjuvant chemoradiation (nCRT) is low, thus requiring therapy optimization. The Hedgehog (HH) pathway has been i...

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Detalles Bibliográficos
Autores principales: Wang, Da, Nagle, Peter W., Wang, Helena H., Smit, Justin K., Faber, Hette, Baanstra, Mirjam, Karrenbeld, Arend, Chiu, Roland K., Plukker, John Th.M., Coppes, Robert P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627376/
https://www.ncbi.nlm.nih.gov/pubmed/31200527
http://dx.doi.org/10.3390/cancers11060821