Cargando…

Hedgehog Pathway as a Potential Intervention Target in Esophageal Cancer

Esophageal cancer (EC) is an aggressive disease with a poor prognosis. Treatment resistance is a major challenge in successful anti-cancer therapy. Pathological complete response after neoadjuvant chemoradiation (nCRT) is low, thus requiring therapy optimization. The Hedgehog (HH) pathway has been i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Da, Nagle, Peter W., Wang, Helena H., Smit, Justin K., Faber, Hette, Baanstra, Mirjam, Karrenbeld, Arend, Chiu, Roland K., Plukker, John Th.M., Coppes, Robert P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627376/ https://www.ncbi.nlm.nih.gov/pubmed/31200527 http://dx.doi.org/10.3390/cancers11060821

Ejemplares similares

Addition of HER2 and CD44 to (18)F-FDG PET–based clinico-radiomic models enhances prediction of neoadjuvant chemoradiotherapy response in esophageal cancer
por: Beukinga, Roelof J., et al.
Publicado: (2020)

Generation and Differentiation of Adult Tissue-Derived Human Thyroid Organoids
por: Ogundipe, Vivian M.L., et al.
Publicado: (2021)

Purification and Ex Vivo Expansion of Fully Functional Salivary Gland Stem Cells
por: Nanduri, Lalitha S.Y., et al.
Publicado: (2014)

Role of mTOR through Autophagy in Esophageal Cancer Stemness
por: Du, Liang, et al.
Publicado: (2022)

Prognostic Value of the Circumferential Resection Margin in Esophageal Cancer Patients After Neoadjuvant Chemoradiotherapy
por: Hulshoff, J. B., et al.
Publicado: (2015)

Role of immediate early genes in the development of salivary gland organoids in polyisocyanopeptide hydrogels
por: Schaafsma, Paulien, et al.
Publicado: (2023)

A Critical Appraisal of Circumferential Resection Margins in Esophageal Carcinoma
por: Pultrum, Bareld B., et al.
Publicado: (2009)

Mouse parotid salivary gland organoids for the in vitro study of stem cell radiation response
por: Serrano Martinez, Paola, et al.
Publicado: (2020)

ASO Author Reflections: Pathologic Complete Response of Extended CROSS Criteria Patients with Esophageal Cancer
por: Wang, H. H., et al.
Publicado: (2020)

Autophagy induction during stem cell activation plays a key role in salivary gland self-renewal
por: Orhon, Idil, et al.
Publicado: (2021)

The sentinel node procedure in colon carcinoma: a multi-centre study in The Netherlands
por: Kelder, Wendy, et al.
Publicado: (2007)

ΔNp73 Enhances Promoter Activity of TGF-β Induced Genes
por: Niemantsverdriet, Maarten, et al.
Publicado: (2012)

Rescue of Salivary Gland Function after Stem Cell Transplantation in Irradiated Glands
por: Lombaert, Isabelle M. A., et al.
Publicado: (2008)

Better Survival in Patients with Esophageal Cancer After Surgical Treatment in University Hospitals: A Plea for Performance by Surgical Oncologists
por: Verhoef, Christian, et al.
Publicado: (2007)

Current and Future Perspectives of the Use of Organoids in Radiobiology
por: Nagle, Peter W., et al.
Publicado: (2020)

Effectiveness of a minimal psychological intervention to reduce mild to moderate depression and chronic fatigue in a working population: the design of a randomized controlled trial
por: Aelfers, Ed, et al.
Publicado: (2013)

A Review of Hedgehog Signaling in Radioresistant Esophageal Cancer: Potential Treatment Target
por: Ma, Li, et al.
Publicado: (2023)

Effect of Extending the Original CROSS Criteria on Tumor Response to Neoadjuvant Chemoradiotherapy in Esophageal Cancer Patients: A National Multicenter Cohort Analysis
por: Wang, Helena Hong, et al.
Publicado: (2020)

ASO Author Reflections: Implementation of Age and Co-morbidity in the Treatment Guideline of Patients with Esophageal Squamous Cell Carcinoma
por: Faiz, Z., et al.
Publicado: (2019)

NEOadjuvant therapy monitoring with PET and CT in Esophageal Cancer (NEOPEC-trial)
por: van Heijl, Mark, et al.
Publicado: (2008)

Dihydroartemisinin Sensitizes Esophageal Squamous Cell Carcinoma to Cisplatin by Inhibiting Sonic Hedgehog Signaling
por: Cui, Wei, et al.
Publicado: (2020)

ASO Author Reflections: Diagnostic Significance of Extramural Venous Invasion in Patients with Locally Advanced Esophageal Cancer
por: Faiz, Zohra, et al.
Publicado: (2018)

Extended Esophagectomy in Elderly Patients with Esophageal Cancer: Minor Effect of Age Alone in Determining the Postoperative Course and Survival
por: Pultrum, B. B., et al.
Publicado: (2010)

Effect of Extending the Original Eligibility Criteria for the CROSS Neoadjuvant Chemoradiotherapy on Toxicity and Survival in Esophageal Cancer
por: de Heer, E. C., et al.
Publicado: (2017)

Krüppel-like Factor 5 Promotes Sonic Hedgehog Signaling and Neoplasia in Barrett's Esophagus and Esophageal Adenocarcinoma
por: Ng, Christopher K., et al.
Publicado: (2019)

Hedgehog inhibition mediates radiation sensitivity in mouse xenograft models of human esophageal adenocarcinoma
por: Teichman, Jennifer, et al.
Publicado: (2018)

Esophageal stenting with minimally-invasive surgical intervention for delayed spontaneous esophageal perforation
por: Chiu, Chien-Hung, et al.
Publicado: (2023)

Prediction of Non-Response to Neoadjuvant Chemoradiotherapy in Esophageal Cancer Patients with (18)F-FDG PET Radiomics Based Machine Learning Classification
por: Beukinga, Roelof J., et al.
Publicado: (2022)

Thyroid cancer in a patient with a germline MSH2 mutation. Case report and review of the Lynch syndrome expanding tumour spectrum
por: Stulp, Rein P, et al.
Publicado: (2008)

Circular RNAs in Hedgehog Signaling Activation and Hedgehog-Mediated Medulloblastoma Tumors
por: Azatyan, Ani, et al.
Publicado: (2021)

Correction: Hedgehog inhibition mediates radiation sensitivity in mouse xenograft models of human esophageal adenocarcinoma
por: Teichman, Jennifer, et al.
Publicado: (2019)

Template-Free Synthesis of Nanoporous Nickel and Alloys as Binder-Free Current Collectors of Li Ion Batteries
por: Lu, Liqiang, et al.
Publicado: (2018)

Exosomal Sonic Hedgehog derived from cancer‐associated fibroblasts promotes proliferation and migration of esophageal squamous cell carcinoma
por: Zhao, Guiping, et al.
Publicado: (2020)

Inhibitors of Hedgehog Acyltransferase Block Sonic Hedgehog Signaling
por: Petrova, Elissaveta, et al.
Publicado: (2013)

Porphyromonas gingivalis secretion leads to dysplasia of normal esophageal epithelial cells via the Sonic hedgehog pathway
por: Jia, Xueting, et al.
Publicado: (2022)

Channeling hedgehogs
por: Wells, William A.
Publicado: (2002)

Hedgehog Zoonoses
por: Behr, Melissa
Publicado: (2005)

Hedgehog Zoonoses
por: Riley, Patricia Y., et al.
Publicado: (2005)

Justice for hedgehogs /
por: Dworkin, Ronald

Agonizing Hedgehog
por: Weitzman, Jonathan B
Publicado: (2002)

Cannot write session to /tmp/vufind_sessions/sess_g6r7hlt0ev39n66eem45jq14pm