Cargando…

ERBB2 Regulates MED24 during Cancer Progression in Mice with Pten and Smad4 Deletion in the Pulmonary Epithelium

ERBB2 is an oncogenic driver with frequent gene mutations and amplification in human lung tumors and is an attractive target for lung cancer therapy. However, target therapies can be improved by understanding the in vivo mechanisms regulated by ERBB2 during lung tumor development. Here, we generated...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Jian, Wang, Tianyuan, Willson, Cynthia J., Janardhan, Kyathanahalli S., Wu, San-Pin, Li, Jian-Liang, DeMayo, Francesco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627404/
https://www.ncbi.nlm.nih.gov/pubmed/31248101
http://dx.doi.org/10.3390/cells8060615