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A Novel Role for Polycystin-2 (Pkd2) in P. tetraurelia as a Probable Mg(2+) Channel Necessary for Mg(2+)-Induced Behavior

A human ciliopathy gene codes for Polycystin-2 (Pkd2), a non-selective cation channel. Here, the Pkd2 channel was explored in the ciliate Paramecium tetraurelia using combinations of RNA interference, over-expression, and epitope-tagging, in a search for function and novel interacting partners. Upon...

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Detalles Bibliográficos
Autores principales: Valentine, Megan S., Yano, Junji, Van Houten, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627415/
https://www.ncbi.nlm.nih.gov/pubmed/31207979
http://dx.doi.org/10.3390/genes10060455