Size and Flexibility Define the Inhibition of the H3N2 Influenza Endonuclease Enzyme by Calix[n]arenes

Inhibition of H3N2 influenza PA endonuclease activity by a panel of anionic calix[n]arenes and β-cyclodextrin sulfate has been studied. The joint experimental and theoretical results reveal that the larger, more flexible and highly water-soluble sulfonato-calix[n]arenes have high inhibitory activity...

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Detalles Bibliográficos
Autores principales: Tauran, Yannick, Cerón-Carrasco, José Pedro, Rhimi, Moez, Perret, Florent, Kim, Beomjoon, Collard, Dominique, Coleman, Anthony W., Pérez-Sánchez, Horacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627454/
https://www.ncbi.nlm.nih.gov/pubmed/31163674
http://dx.doi.org/10.3390/antibiotics8020073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627454/
https://www.ncbi.nlm.nih.gov/pubmed/31163674
http://dx.doi.org/10.3390/antibiotics8020073

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