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Fine Mapping of Glutamate Decarboxylase 65 Epitopes Reveals Dependency on Hydrophobic Amino Acids for Specific Interactions

Characterization of multiple antibody epitopes has revealed the necessity of specific groups of amino acid residues for reactivity. This applies to the majority of antibody–antigen interactions, where especially charged and hydrophilic amino acids have been reported to be essential for antibody reac...

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Detalles Bibliográficos
Autores principales: Valdarnini, Niccolò, Holm, Bettina, Hansen, Paul, Rovero, Paolo, Houen, Gunnar, Trier, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627456/
https://www.ncbi.nlm.nih.gov/pubmed/31207885
http://dx.doi.org/10.3390/ijms20122909