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In-depth Analysis of the Lid Subunits Assembly Mechanism in Mammals

The 26S proteasome is a key player in the degradation of ubiquitinated proteins, comprising a 20S core particle (CP) and a 19S regulatory particle (RP). The RP is further divided into base and lid subcomplexes, which are assembled independently from each other. We have previously demonstrated the as...

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Detalles Bibliográficos
Autores principales: Bai, Minghui, Zhao, Xian, Sahara, Kazutaka, Ohte, Yuki, Hirano, Yuko, Kaneko, Takeumi, Yashiroda, Hideki, Murata, Shigeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627463/
https://www.ncbi.nlm.nih.gov/pubmed/31159305
http://dx.doi.org/10.3390/biom9060213